BioMEA System

A modular 256-channel Micro Electrode Array (MEA) system for STIMULATION and ACQUISITION. MEA biochips are well recognized as a powerful tool for exploring the dynamics of large neural network. BioMEA provides a choice of 3 models supporting 64, 128 or 256 electrodes and also a large choice of MEA ranging from planar to unique 3D electrodes (for an optimized tissue penetration).

BioMEA-256 was specified and tested in collaboration with CNRS and University of Bordeaux, UMR5228, France, and developed under ‘Licence CEA-LETI-MINATEC’, with the collaboration of DTBS “Departement des micro-technologies pour la Biologie et la Sante“ and DCIS “Departement Conception et Integration Systeme”, CEA-LETI-MINATEC, Grenoble, France.

General specifications:
• In vitro electrophysiology
• Control of 256 electrodes : stimulation/acquisition
• One software for stimulation and acquisition
• Real time visualization
• Online filtering
• Current stimulation
• Compatible with inverted and upright microscope
• Matlab interfacing
• Spike2 compatibility
• Easy design of stimuli patterns
Applications:
• Drug Discovery and Development
• Neuroscience
• Cells culture
• Cardiac electrophysiology


For more information, please click here to download the BioMEA brochure (PDF).

MEA60 Biochips for Electrophysiology

Multi-electrode array (MEA) biochips are used to stimulate and record extracellular electrical activity of excitable biological tissue from as many as 60 recording sites simultaneously. In most cases, single unit activity and/or slow field potentials are recorded in preparations such as dissociated cell cultures (neurons, heart muscle cells) and organotypic or acute tissue slices (brain, spinal cord, retina, etc.). In the drug discovery process, the use of MEA technology in secondary screening will provide more in depth information on the systems biology response.

The Ayanda™ MEA biochips are fabricated on transparent microchips and are adapted to the commercially available MEA60 signal amplification and data acquisition system from Multi Channel Systems MCS (Reutlingen, Germany). We offer various micro-electrode geometries on the Ayanda™ MEA biochips ranging from planar to 3D tip-shaped electrodes.

The unique Ayanda™ 3D MEA biochip, which includes tip-shaped micro-electrodes, enables improved and more reliable electrophysiological experimentation with acute brain slices. The publication by M. Heuschkel et al., J. Neurosci. Methods 114 (2002) 135-148 provides a detailed discussion of this product and its characteristics.

Custom-designed MEA Biochips

We can also offer upon request user-specific solutions in terms of MEA-layout configuration. Ayanda™ MEA biochips can be adapted to other amplification and data acquisition systems. We would be pleased to provide a quote upon request. Click here to find out more about customised MEA biochips.

More Information

Please find more information about the Ayanda™ MEA biochips at the following links:
• Available single-well MEA biochips
  
• Multi-well MEA biochips
• MEA biochips applications
  
• MEA biochip technology references
  
  
• Please find more documentation on our download page